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KMID : 0370219630070040086
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Yakhak Hoeji
1963 Volume.7 No. 4 p.86 ~ p.91
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Pharmacological Study of Components from Lycoctonum Sp. Ⅰ
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Abstract
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Crystal A and B were isolated from L. pseudo-laeve Nakai and their pkarmacological action was observed. Crystal A, in dose of 5×10^(-4)∼5×10^(-5) g/㎖, stimulated excised frog heat but at 2.5×10^(-6) ~0.5×10^(-5) g/㎖ of cystal B, depressant effect was observed. Mild stimulation of rhythmicity of exeised rabbit intestine was produced by 1×10^(-4) g/㎖ of crystal A and 2×10^(-4) g/㎖ of crystal B. Harked depression of tone was produced by 2×10^(-4) g/㎖ of crystal A, antagonizing by pilocarpine. Crystal B(4×10^(-4) gm/ℓ) produced mild stimulation, followed by depression of tone. No curare-like action on excised frog abdominal muscle was elicited with both susbtances.
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KEYWORD
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